The Joint Program Executive Office for Chemical, Biological, Radiological and Nuclear Defense (JPEO-CBRND) manages our nation’s investments in chemical, biological, radiological, and nuclear (CBRN) defense equipment and medical countermeasures.

The JPEO-CBRND leads, manages, and directs the acquisition, fielding and sustainment of CBRN sensors, protective equipment, medical countermeasures, specialized equipment for U.S. Special Forces, integration and information management systems, and defense enabling biotechnologies. The organization also works closely with various government agencies that need CBRN defense equipment. The JPEO-CBRND is one of the Chemical and Biological Defense Program’s four components. The Deputy Assistant Secretary of Defense for Chemical and Biological Defense oversees this program. The Assistant Secretary of the Army for Acquisition, Logistics, and Technology (ASA(ALT)), who is the Army Acquisition Executive, delegates JPEO-CBRND’s acquisition authority.

Learn more about the Joint Project Management Offices for CBRN Protection, CBRN Medical, CBRN Sensors, and CBRN SOF, and the Joint Project Lead Offices for CBRND Enabling Biotechnologies and CBRN Integration.

Learn more about the JPEO-CBRND

Our Mission

Provide integrated layered chemical, biological, radiological, and nuclear defense capabilities to the Joint Force across Combined Joint All-Domain Operations

Our Vision

A resilient Joint Force enabled to fight and win unencumbered by a chemical, biological, radiological, or nuclear environment; championed by innovative, agile, results-oriented acquisition professionals

Partnering Benefits


Work with the JPEO-CBRND on providing solutions that protect the Joint Force and the Warfighter from weapons of mass destruction. Help us achieve our vision of a resilient Joint Force that's enabled to fight and win unencumbered by CBRN environments.

Innovative Contracting Experience iconInnovative Contracting Experience

Our Other Transactional Authority (OTA) agreements enable enhanced communications and support innovation. 

Agile Execution iconAgile Execution

We face a complex threat environment, so we need the partnership and support of industry and academia to help us innovate at the speed of relevancy for our current CBRN defense environments.

Share iconShare Your Latest Insights with Government

The JPEO-CBRND is eager to learn more about the latest innovations, capabilities and insights to help support the Joint Force and protect our Warfighters. 

Keep Current iconKeep Current on the CBRND Industrial Base’s Needs

Gain insight into the way ahead for our organization as well as our CBRND partners.

Modernize iconHelp Modernize the Joint Force 

Help establish and refine the long-term vision for CBRND capabilities.

Speed iconDevelopment at the Speed of Relevancy

Help the JPEO-CBRND tackle the R&D needs on the horizon.

Featured Technologies

Joint Service General Purpose Mask (JSGPM)

Joint Service General Purpose Mask (JSGPM)


Next Generation Diagnostics System 1 (NGDS 1)

Next Generation Diagnostics System 1 (NGDS 1)


Nuclear, Biological, Chemical Reconnaissance Vehicle

Nuclear, Biological, Chemical Reconnaissance Vehicle (NBCRV)



Two soldiers wearing full protective gear adjust settings and learn to use the chemical vapor detector.

Modular Next Generation Chemical Detector to Provide Integrated Layered CBRN Defense to Joint Force

Jun. 05, 2024

Quickly detecting the presence of chemical agents is critical to joint force survivability. Knowing that...
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Soldiers put together a cart.

CBRN DRS Nears FOC - It's Not Easy as 1,2,3

May. 23, 2024

The modern battlespace is dynamic. As conflicts in Ukraine and Israel unfold and perpetual threats from our...
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American flags against a blue sky background

JPEO-CBRND Research Featured in Nature: World’s Leading Multidisciplinary Science Journal

May. 08, 2024

In a groundbreaking development for addressing future viral pandemics, an interagency team of researchers have...
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A map of the world

Around the World: JPEO-CBRND Gathers Global Data to Enhance Threat Detection Capabilities

Apr. 15, 2024

In recent years, the public has become more familiar with rapid biological diagnostic technologies for...
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The People Behind the Mission: A Q&A with the Women of JPL CBRND Enabling Biotechnologies

Mar. 22, 2024

March is Women’s History Month, so we caught up with some of our leading ladies from the Joint Project Lead...
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The graphic shows the various elements included in the decision tree for the GUIDE program. The slide is broken in two halves (right and left). The left upper corner shows a microbe, models of manufacturability, efficacy, safety data and pharmacodynamics. On the right side of the slide shows how the GUIDE program will help pair these things for the optimal output through the GUIDE program's capabilities.

GUIDE Program Prepares DOD to Defend Against the Unknown

Feb. 27, 2024

Significant biological events can take different shapes and sizes, from disease to intentional poisons and...
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